The greater incidence of dyslipidaemia in patients with schizophrenia has been well documented.[Correll, 2007; Hsu et al., 2012; Solberg et al., 2016] There is ongoing debate regarding whether lipid disturbance in schizophrenia is a component of the disease or a result of antipsychotic therapy, and to what extent these two factors contribute to the lipid profile seen in patients with schizophrenia.[Hsu et al., 2012; Correll, 2007]
References:
Correll CU. Balancing efficacy and safety in treatment with antipsychotics. CNS Spectr 2007; 12 (10 Suppl 17): 12–20, 35.
Hsu JH, Chien IC, Lin CH, Chou YJ, Chou P. Hyperlipidemia in patients with schizophrenia: a national population-based study. Gen Hosp Psychiatry 2012; 34 (4): 360–367.
Solberg DK, Bentsen H, Refsum H, Andreassen OA. Lipid profiles in schizophrenia associated with clinical traits: a five year follow-up study. BMC Psychiatry 2016; 16: 299.