Key message: Negative feelings towards medication are associated with lower scores in both affect and self-esteem.
Background
- Cross-sectional study investigating patients aged 19–60 (n=80) with schizophrenic disorder according to International Classification of Diseases 10th revision (ICD-10) criteria who had a duration of illness >1 year and whose discharge from an inpatient unit had been ≥6 weeks earlier.[Hofer et al., 2004]
- The aim of the study was to investigate the relationship between antipsychotic-induced adverse events and subjective quality of life (QoL).[Hofer et al., 2004]
- Various rating scales were used: Positive and Negative Syndrome Scale (PANSS), St. Hans Rating Scale for Extrapyramidal Syndromes, the UKU Side Effect Rating Scale, the Drug Attitude Inventory (DAI), and the Lancashire Quality of Life Profile.[Hofer et al., 2004]
- The combined effects of sociodemographic variables, psychopathology, type of antipsychotic medication, antipsychotic-induced adverse events, and attitude toward medication, on QoL were analysed with multiple linear regression analysis (summarised on the slide).[Hofer et al., 2004]
Reference:
Hofer A, Kemmler G, Eder U, et al. Quality of life in schizophrenia: the impact of psychopathology, attitude toward medication, and side effects. J Clin Psychiatry 2004; 65 (7): 932–939.