The slide summarises the main phases of schizophrenia, and the frequency of patients transitioning between phases based on a wide-ranging literature review.[Carbon & Correll, 2014] After reviewing the literature, the authors conclude that a key problem in understanding the course of schizophrenia is the differences in definitions and concepts used to identify the various stages.[Carbon & Correll, 2014] However, the review did identify the duration of untreated psychosis as a modifiable risk factor that clinicians can act upon now, as well as nonadherence to antipsychotic medications, and certain comorbidities.[Carbon & Correll, 2014]
Reference:
Carbon M, Correll CU. Clinical predictors of therapeutic response to antipsychotics in schizophrenia. Dialogues Clin Neurosci 2014; 16 (4): 505–524.