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non-motors sympt figs 1-2 – slide 1
Braak staging of Parkinson’s disease

At a physiological level, PD is characterised by the loss of neurons in specific regions of the brain and a spreading of Lewy pathology.[Halliday et al., 2014] However, these do not necessarily always go together; many regions with a…

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non-motors sympt figs 1-2 – slide 2
Distribution of α-synuclein pathology in Parkinson’s disease

The Lewy pathology and aggregated α-synuclein proteins associated with PD are not confined to the central nervous system (CNS); they can also be found in the peripheral nervous system at various sites around the body, such as the skin,…

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