Slide Decks on Migraine

Migraine is a chronic neurological disease characterised by episodic attacks of head pain.  It is a burdensome condition and one of the commonest neurological diseases worldwide.

Get an introduction to what is currently known about migraine by going through our slide decks. You can scroll through the slides, read the presenter notes or download the slides and use them for your own presentations.

History, Definitions, and Diagnosis

The perception of migraine has changed substantially through the last century.  This slide deck explores basic migraine concepts and definitions.  Go to the slide deck.

Epidemiology and Burden

This slide deck describes current knowledge on the economic and general burden of migraine. You will also find a brief introduction to the risk factors for the onset of migraine. Go to the slide deck.

Neurobiology and Aetiology

This slide deck offers insight into the neurobiology and aetiology of migraine and discusses pain and nociception, the pathology of migraine and the brain regions involved in migraine. Go to the slide deck.

Course, Natural History, and Prognosis

In this slide deck you will find descriptions and illustrations of migraine attacks and triggers, including the four phases of a migraine attack. The slide deck also outlines the evolution of migraine from episodic to chronic and gives an introduction to migraine prognosis. Go to the slide deck.


Determining the relationship between migraine and a comorbid condition is complicated. This slide deck discusses in detail the presence of comorbidity in Migraine.

Go to the slide deck.

Treatment Principles

In this slide deck you will find basic concepts and definitions related to modern treatment approaches such as the use of analgesics and NSAIDs, as well as more targeted therapies, such as triptans and CGRP medications. Go to the slide deck.

Download Illustrations & Figures on Migraine

Migraine is a complex spectrum disorder. The differences between people with episodic and chronic migraine highlight the need for treatments to be tailored to each group. Browse our library of downloadable psychiatry and neurology illustrations – everything you need for your presentations. This resource includes illustrations and figures on a range of key concepts or neuroscience facts.

Pathways involved in the regulation of pain in migraine
Pharmacological targets for CGRP inhibition
The image shows a schematic of how cortical spreading depression might interact with the trigeminovascular system in one proposed model of migraine pathology.
Various clinical data demonstrate the crucial role CGRP plays in migraine pathology, and there are several different methods of blocking CGRP activity to treat migraine attacks.
ICHD-3 definitions for episodic and chronic migraine
Migraine attacks can be broken down into four phases: prodrome, aura, headache, and postdrome, as shown in the image.

Watch the Video on Migraine

Professors Lars Edvinsson, Peter Goadsby, Michael Moskowitz and Jes Olesen were awarded The Brian Prize in 2021 for their outstanding research on the causes and treatment of migraine.

Neurotorium and The Brain Prize partners on making educational resources on the winning topic available to all interested in learning more. You can read about the award-winning research on migraine at The Brain Prize website.

play_circle Video

Nearly 1 billion people suffer from migraine. In 2021, The Brain Prize – the world’s largest brain research prize – was awarded to Professors Lars Edvinsson, Peter Goadsby, Michael Moskowitz and Jes Olesen for their ground-breaking work on the causes and treatment of migraine.

Neurotorium and The Brain Prize collaborate on making this exceptional research available to clinicians who are working with matters of the brain in their daily lives.

In this documentary film, developed by the team behind The Brain Prize at the Lundbeck Foundation, you can learn more about migraine and the research that led to the brain prize in 2021, and you hear from a patient who suffers from the rarer condition of chronic migraine.

3D Brain Atlas

Some areas of the brain seem to be particularly related to migraine:

  • The trigeminal nerve, the fifth cranial nerve, together with the brain stem, forms the trigeminal complex. Several lines of research point to the importance of this complex for migraine.
  • Thalamus appears to be important for several processes underlying migraine, such as allodynia and central sensitisation.