Download Slide Decks on Parkinson’s Disease

Parkinson’s Disease (PD) is the second-most common neurodegenerative disorder, after Alzheimer’s Disease. PD is a chronic, progressive, neurodegenerative condition that mainly affects elderly people. The clinical effects of Parkinson’s Disease are visually obvious, but the underlying pathology of PD is still not fully understood. 

In each slide deck, you will encounter a topic introduction and delve into essential concepts related to Parkinson’s disease. Our slide decks encompass a variety of subjects, including genetic risk factors for Parkinson’s disease, the challenges of managing non-motor symptoms, and motor complications such as dyskinesia and motor fluctuations.

History, Definitions, and Diagnosis

In this slide deck, the history of Parkinson’s disease is presented together with a description of the cardinal symptoms of the disease, diagnostic criteria, biomarkers and commonly used scales. Go to the slide deck.

Epidemiology and Burden

This presentation covers the prevalence of Parkinson’s Disease across different global regions and describes the substantial burden the disease places on the patient and caregivers. Go to the slide deck.

Course, Natural History, and Prognosis

In this slide deck, the course, natural history and prognosis of PD are discussed, including infographics on prodromal PD as well as the stages of PD. Go to the slide deck.

Non-motor Symptom Complex and Comorbidities

Non-motor symptoms are reported by nearly all patients with Parkinson’s disease. In this slide deck, non-motor symptoms, quality of life and the comorbidities of Parkinson’s disease are discussed. Go to the slide deck.

Neurobiology and Aetiology

This slide deck covers the neurobiology and aetiology of Parkinson’s Disease (PD). Pathogenetic details, including underlying common pathways and treatment designs based on the pathogenesis model, are discussed. Go to the slide deck.

Treatment Principles

This slide deck covers the current treatment and medication options for Parkinson’s Disease. Infographics on medications, deep brain stimulation, disease modification and gene- and cell-based therapies are explored. Go to the slide deck.

Read Articles on Parkinson’s Disease

Our selected articles will delve into these facets of Parkinson’s disease, offering insights into the diverse nature of non-motor symptoms, their impact on patients, and the potential for improved management.

Watch the Videos on Parkinson’s Disease

Get insights on Parkinson’s disease through our videos. Understand the complexities of Parkinson’s Disease pathology and explore the mechanics of movement with The Brain Prize Explainer. Elevate your understanding with expertly curated content.

Understanding the Pathology of Parkinson’s Disease

This video explains the Pathology of Parkinson’s Disease, the role of α-synuclein in the pathogenesis, motor dysfunction in Parkinson´s Disease and treatment hereof. Go to video.

The Brain Prize Explainer – How We Move

In this documentary film, developed by the team behind The Brain Prize at the Lundbeck Foundation, you can learn more about how we mammalians move and the research that led to The Brain Prize in 2022. Go to video.

Key Genes Identified in AD and PD

In this video, Professor John Hardy, UCL Institute of Neurology, discusses key genes identified in Alzheimer’s disease and critical genes identified in Parkinson’s disease. Go to video.

Download Illustrations & Figures on Parkinson’s Disease

View an illustration of the bidirectional interplay between the brain and the gut, involving pathways such as the vagus nerve and bloodstream. Factors contributing to Parkinson’s disease development encompass aging-related processes, alpha-synuclein aggregation and spread, the gut bacterial microbiome and its metabolic activities, gut barrier integrity, inflammation, environmental influences, host genetic factors, and possibly chance effects. See a schematic illustration depicting how the gut-brain axis may contribute to the spread of alpha-synuclein pathology below.

Schematic illustration of how the gut-brain axis may contribute to the spread of alpha-synuclein pathology
Bidirectional interplay between the brain and the gut includes the vagus nerve pathway, and non-vagus nerve pathways such as the bloodstream. Important factors associated with the development of PD include ageing-related processes, aggregation and spread of alpha-synuclein, gut bacterial microbiome and their metabolic activities, gut barrier disruption, inflammation, environmental influences, host genetic factors, and probably chance effects.
This picture illustrates potential non-motor features associated with Parkinson’s disease