Various clinical data demonstrate the crucial role CGRP plays in migraine pathology, and there are several different methods of blocking CGRP activity to treat migraine attacks.

1. Gepants – CGRP receptor antagonists, which bind to the CGRP receptor and prevent signalling.

2. Anti-CGRP antibodies, which prevent CGRP interacting with its receptor.

3. Anti-CGRP receptor antibodies, which bind to the CGRP receptor and prevent signalling.

Read more about anti-CGRP therapies and their mechanism of action

file_download Download