Migraine is a burdensome condition and one of the commonest neurological diseases worldwide. This slide deck describes current knowledge on the economic and general burden of migraine. You will also find a brief introduction to the risk factors for the onset of migraine.

This slide deck has been developed for Neurotorium in collaboration with Cambridge Medical – A Prime Global agency and Bjarke Ebert H. Lundbeck A/S. Reviewed by Clinical Prof. Dawn C. Buse, Albert Einstein College of Medicine.

 

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slide deck

Introduction

Migraine - epidemiology and burden_slide1
Migraine - Epidemiology and burden
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Migraine – Epidemiology And Burden Slide2
Migraine epidemiology

Migraine is a burdensome condition.[GBD, 2017; Steiner et al., 2018; Buse et al., 2020] The Migraine in America Symptoms and Treatment (MAST) study was an internet-based survey that questioned people with migraine about their headaches.[Buse et al., 2020] The results sho…

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Prevalence of migraine

Migraine – Epidemiology And Burden Slide3
Prevalence of migraine
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Migraine and headache in the WHO GBD study

The Global Burden of Disease (GBD) study takes a standardised approach to estimating incidence, prevalence, and years lived with disability (YLD) of various diseases and health states, often segmenting the data by age, sex, year, and geography.[GBD, 2017] An analysis of …

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Migraine – Epidemiology And Burden Slide5
Prevalence of migraine with and without aura

Although estimates vary, approximately 20% of patients with migraine experience aura, albeit not during every attack.[Queiroz et al., 2011; Weatherall, 2015] The aura of migraine is usually visual, and can include flashes of light, moving patterns, or partial loss of vis…

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Migraine – Epidemiology And Burden Slide6
Prevalence of migraine by age and sex

There are wide variations in the reported prevalence of migraine, due to differences in factors such as study methodology, age of participants, and geography.[Lipton & Bigal, 2005] The Global Burden of Disease (GBD) study found that headaches were most burdensome in wome…

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Migraine – Epidemiology And Burden Slide7
Female versus male prevalence of migraine

Migraine has a higher prevalence among women than it does among men.[Weatherall, 2015; Vetvik & MacGregor, 2017] A number of studies have found that women with migraine report a higher headache-related disability than men.[Vetvik & MacGregor, 2017] It has been argued tha…

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Migraine – Epidemiology And Burden Slide8
Migraine as a global health crisis – the top cause of disability in the under 50s

The Eurolight study was a European survey that gathered data from patients with headache in Austria, France, Germany, Ireland, Italy, Lithuania, Luxembourg, the Netherlands, Spain and the United Kingdom.[Katsarava et al., 2018] Of the 9,247 respondents, approximately a t…

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Risk factors for the onset of migraine

Migraine – Epidemiology And Burden Slide9
Risk factors for the onset of migraine
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Genetics

Various approaches have been taken to unravel the complex genetics of headache and migraine disorders.[Sutherland et al., 2019] Linkage mapping analysis can trace genetic markers and candidate genes in family pedigrees of monogenic headache disorders.[Sutherland et al., …

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Migraine – Epidemiology And Burden Slide11
Lifestyle factors and migraine risk

The negative health effects of physical inactivity, alcohol overuse and misuse, smoking, and obesity are widely known. However, the interaction of these lifestyle factors with migraine risk is relatively poorly studied.[Hagen et al., 2018] In the two large-scale longitud…

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Migraine – Epidemiology And Burden Slide12
Migraine attack triggers

Various different migraine triggers have been identified, including emotional, physical, dietary, and environmental factors.[Migraine Trust; Pavlovic et al., 2014; Park et al., 2016; Sarchielli, 2006; Turner et al., 2019; Wöber et al., 2006] Migraine triggers are a compl…

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