Index for
slide deck
Introduction
Epidemiology and burden
Global epidemiology of schizophrenia
Global epidemiology of schizophrenia
Global prevalence and incidence of schizophrenia
The GBD study has quantified the burden of 371 diseases, including schizophrenia, across 204 countries and territories, using metrics such as ‘years lived with a disability’, ‘disability-adjusted life-years’, ‘years of life lost to premature mortality’, and ‘healthy life …
Prevalence and incidence of schizophrenia by region
To describe the burden of schizophrenia regionally, the GBD study has grouped 204 countries into 21 GBD regions according to socioeconomic similarity and geographical proximity.2
Regions with the highest ASIRs include Australasia (20.2 per 100,000) and East Asia (18.3 per…
Prevalence and incidence of schizophrenia over time and by sociodemographic index
Prevalence and incidence of schizophrenia by sex
GBD data for 2021 reported 659,000 (95% UI: 545,000, 791,000) incident cases of schizophrenia in males and 564,000 (95% UI: 464,000, 681,000) in females; this translated into an ASIR of 16. per 100,000 (95% UI: 13.6, 19.7) for males and 14.4 per 100,000 (95% UI: 11.8, 17…
Prevalence and incidence of schizophrenia by age
A GBD 2021 analysis among young people (aged 10–24 years) across the G20 countries revealed schizophrenia incidence was generally higher in males, although prevalence showed more variable sex differences across countries.3
In an analysis of people aged 15–39 years, the GB…
Global burden of schizophrenia
Global burden of schizophrenia
Global burden of disability due to schizophrenia
In the GBD study, each death can only be assigned one cause. Schizophrenia is not listed as a cause of death; deaths in people with schizophrenia are recorded due to causes such as suicide or other physical illness. Consequently, the GBD study assigns zero deaths to schiz…
Schizophrenia burden by region
Schizophrenia burden by sex
Similar to 2019 estimates, the GBD study reported higher ASDRs for males (189.0 per 100,000 [95% UI: 139.9, 243.7]) with schizophrenia than females (166.4 per 100,000 [95% UI: 122.8, 213.9]) in 2021, suggesting consistent temporal trends.5
A GBD analysis of 2021 data for …
Age patterns in the disability burden of schizophrenia
A Danish study of over 6.9 million residents aimed to calculate YLD for 18 mental and substance use disorders.2 Schizophrenia was associated with 225.0 (95% CI: 190.0, 258.0) YLD per 100,000 person-years in females and 322.6 (274.1, 370.7) YLD per 100,000 person-years in …
Disability burden due to schizophrenia over time and by SDI
The calculation of GBD data is based on the data available for each country, which means the accuracy of GBD data depends heavily on the quality and quantity of data used in the algorithm.3 The lowest epidemiological data coverage was found in data from countries with low…
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Schizophrenia remains one of psychiatry’s most complex disorders due to its multifactorial etiology, involving interacting biological, psychological, and environmental factors.
Schizophrenia is a severe psychiatric disorder that has a profound effect on the individuals affected, their caregivers, and society.
Schizophrenia is associated with interacting genetic, environmental, and neurobiological factors that affect brain development, neurotransmission, immune function, and neural circuits.