Schizophrenia - Epidemiology and Burden

The World Health Organization identified schizophrenia as one of the world’s 20 leading causes of disability. The presentation covers the impact of schizophrenia on patients and their caregivers, and its prevalence across different global regions. This slide deck explores the epidemiology and burden of schizophrenia and includes illustrations of the economic burden of the illness.

This slide deck has been developed in collaboration with the former Lundbeck International Neuroscience Foundation.

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Epidemiology and Burden

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Epidemiology and Burden

Global Impact of Schizophrenia

The World Health Organization identified schizophrenia as 1 of the 20 leading causes of disability in the world in 2004.^{[The global burden of disease, 2004]}

The same report estimated that the worldwide prevalence was more than 21 million people in…

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Schizophrenia – Epidemiology and Burden – slide 4

The morbid risk of schizophrenia increases in relation to the percentage of genes shared with an affected individual

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Schizophrenia – Epidemiology and Burden – slide 5

The negative impact of schizophrenia on patients and their caregivers affects many aspects of life

Key message: Schizophrenia negatively impacts many different aspects of the lives of both patients and their caregivers (e.g. economic, physical health, social aspects).

Background

A community survey that included 697 caregivers and 439 patients with schizophrenia identified the…

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Schizophrenia – Epidemiology and Burden – slide 6

Caregivers of patients with schizophrenia can experience negative changes in their own quality of life

Key message: Decreases in the quality of life of caregivers may be associated with the burden of being a caregiver, lack of social support, course of the disease, and problems with family relationships.

Background^{[Caqueo-Urízar et al., 2009]}

Literature review…

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Schizophrenia – Epidemiology and Burden – slide 7

Inability to function in everyday settings contributes to the high cost of schizophrenia

Key message: Inability of patients to function in everyday settings contributes to the high cost of schizophrenia (both direct costs from caring for patients, and indirect costs from lost employment).

Background

Schizophrenia causes a high degree of disability.…

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Schizophrenia – Epidemiology and Burden – slide 8

Schizophrenia One-Year Incidence Rates From Selected World Studies

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Schizophrenia – Epidemiology and Burden – slide 9

Epidemiology of Schizophrenia in the United States

The 1-year prevalence of schizophrenia in the United States was estimated to be 1.1% of the adult population.^{[Regier et al., 1993]}

37 Population-based studies from 25 countries that reported primary data on deaths in people with schizophrenia were examined.^{[Saha et al.,…}

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Schizophrenia – Epidemiology and Burden – slide 10

Prevalence of Schizophrenia in Asia

Taiwan: A random population of subjects from the National Health Insurance database was used to identify members with ≥1 claim for a principal diagnosis of schizophrenia.^{[Chien et al., 2004]}

China: A random population of subjects from Xinjin County were interviewed face…

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Schizophrenia – Epidemiology and Burden – slide 11

Epidemiology of Schizophrenia in Europe

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Schizophrenia – Epidemiology and Burden – slide 12

Epidemiology of Schizophrenia in Canada

Vanasse and colleagues examined the lifetime prevalence of patients with schizophrenia in Quebec from 1996 to 2006 using public health plan databases. Patients were identified with a hospital discharge or physician claim for schizophrenia.^{[Vanasse et al., 2012]}

Goldner et al estimated…

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