Treatment resistant schizophrenia (TRS) has a severe clinical and economic impact on patients, carers, families and society as the whole. Research on TRS has generated several hypotheses to explain the underlying pathophysiology. This video provides an overview of one such hypothesis.
Related content
Schizophrenia is associated with interacting genetic, environmental, and neurobiological factors that affect brain development, neurotransmission, immune function, and neural circuits.
In this video, Professor Dr. Ana Catalan explores whether psychotic disorders can be prevented and reviews the latest evidence on early intervention in psychosis. She explains how personalized, evidence-based care can enhance quality of life, daily functioning, and long-term recovery for people at risk of or experiencing psychosis.
Schizophrenia is associated with substantial disability, reduced life expectancy, and increased rates of psychiatric and physical comorbidities.