The monovalent alkali metal lithium has been used to treat bipolar disorder for many decades.2 Although the exact mechanism of action is still unclear, lithium has many effects on the brain as outlined on the slide.1,2
References:
1. Alda M. Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics. Mol Psychiatry 2015; 20 (6): 661–670.
2. Kamal ZM, Dutta S, Rahman S, et al. Therapeutic application of lithium in bipolar disorders: a brief review. Cureus 2022; 14 (9): e29332.
3. Gitlin M. Lithium side effects and toxicity: prevalence and management strategies. Int J Bipolar Disord 2016; 4 (1): 27.