Parkinson’s disease is the second most frequent neurodegenerative disorder of ageing after Alzheimer’s disease.
Parkinson’s disease is characterized by 4 cardinal motor symptoms: tremor at rest; rigidity; bradykinesia; and postural instability. This progressive disorder is also associated with cognitive, behavioural, and autonomic impairments causing increased disability and contributing to a loss of independence.
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Professor Dr. Per Borghammer unpacks the brain-first vs body-first model of Parkinson’s disease, exploring distinct pathways of progression from the gut or nose and their potential to drive personalized medicine and innovative treatments.
Professors Shen-Yang Lim and Christoph Correll explore dopamine’s role in Parkinson’s disease and schizophrenia, discussing treatment evolution, side effects, and parallels between the disorders. Access more resources at Neurotorium.org.
The Braak staging scheme is a valuable model for conceptualizing PD progression and categorizes PD into stages of neuropathological changes.