Antagonist binding to the α2 noradrenaline receptor induces noradrenaline release. Binding of an antagonist to the noradrenaline receptor prevents binding of noradrenaline or of an agonist to the receptor and prevents secondary messenger inhibition allowing cell depolarization to occur.
Related content
The pathology of ischaemic stroke is complex, but commonly involves the formation of a clot that travels in the blood to or within the brain and becomes lodged in the blood vessels of the brain (a thromboembolism), which can reduce or block blood flow (an occlusion).
Post-stroke fatigue is an under-recognized NPS, which healthcare professionals should anticipate in patients.
Emotional lability describes episodes of involuntary and uncontrollable crying and/or laughing, outside of socially appropriate circumstances and when it is incongruent with the patient’s emotional state.