Antagonist binding to the α2 noradrenaline receptor induces noradrenaline release. Binding of an antagonist to the noradrenaline receptor prevents binding of noradrenaline or of an agonist to the receptor and prevents secondary messenger inhibition allowing cell depolarization to occur.

file_download Download in HQ

Related content

The Heterogeneity of Depression and Immunometabolic Depression play_circle Video play_circle
The Heterogeneity of Depression and Immunometabolic Depression

Professor Dr. Brenda Penninx discusses the heterogeneity of major depressive disorder, with specific reference to immunometabolic depression

31.03.2025 Depression
image Image Patients with bipolar disorder and comorbidities are typically more complex cases than patients with bipolar disorder without medical or psychiatric comorbidities
Principles of treating patients with bipolar disorder and comorbidities

Patients with bipolar disorder and comorbidities are typically more complex cases than those without medical or psychiatric comorbidities

03.09.2024 Bipolar Disorder
image Image The DSM-5 replaced the DSM-IV-TR ‘mixed episode’ diagnosis with the ‘mixed features’ specifier that can  be applied to a current manic, hypomanic, or  depressive episode in major depressive disorder  and bipolar disorder
Factors associated with mixed features

Factors associated with mixed features includes unemployment among others

03.09.2024 Bipolar Disorder