Migraine is often comorbid with chronic pain.1,2,3 Indeed, migraine and complex regional pain syndrome (CRPS) are thought to share some pathology and clinical characteristics.3
The Norwegian HUNT survey found a strong association between chronic headache and musculoskeletal symptoms and joint pain.1
Chronic headache was more prevalent in participants with musculoskeletal symptoms than those without: OR: 4.6 (95% CI: 4.0, 5.3)1
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Migraine is a prevalent neurological disorder characterized by recurrent and disabling attacks of moderate to severe headache
Migraine affects an estimated 1.1 billions worldwide and ranks as the 2nd leading cause of disability, while being the leading among young adults.
In human models of migraine, a suspected pharmacological migraine trigger is administered either orally or via infusion to a participant with migraine or a healthy volunteer, typically within a double-blinded, randomized, placebo-controlled design