Fear and anxiety are experienced on a spectrum, stretching from basic ‘normal’ emotions to the categorical phenotypes of anxiety disorders.1 Whilst much progress has been made in studying anxiety, it has been proposed that the Research Domain Criteria (RDoC) – that attempt to develop an interdisciplinary science of psychopathology, creating a set of research principles to better investigate mental disorder – may be used to investigate the pathology underlying anxiety disorders, although there are challenges to doing to so.3
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