The systematic literature review outlined on the slide found only eleven studies of the prevalence of bipolar disorder and migraine comorbidity.3 The mean prevalence of migraine among people with bipolar disorder was 30%.3 However, there was much variation in the studies included in the analysis, in study design, sample sizes, and diagnostic criteria, making interpretation of these data a challenge.3 More research is needed to understand the nature of the interaction between bipolar disorder and migraine, and how best to help patients who experience these conditions concurrently.3
References:
1. American Psychiatric Association (APA). Diagnostic and Statistical Manual of Mental Disorders. Fifth edition, text revision. Washington DC: APA; 2022.
2. Fasmer OB. The prevalence of migraine in patients with bipolar and unipolar affective disorders. Cephalalgia 2001; 21 (9): 894–899.
3. Leo RJ, Singh J. Migraine headache and bipolar disorder comorbidity: a systematic review of the literature and clinical implications. Scand J Pain 2016; 11: 136–145.