Two forms of cycles in bipolar disorder have been identified, as shown on slide, the mania-depression-interval cycle and the depression-mania-interval cycle.1

Reference:
1. Koukopoulos A, Reginaldi D, Tondo L, et al. Course sequences in bipolar disorder: depressions preceding or following manias or hypomanias. J Affect Disord 2013; 151 (1): 105–110.