Predictors of functional outcome – examples

This study analysed the trajectories of 261 people after a first episode of psychosis.¹ Four trajectories were broadly identified, as shown on the slide:¹
mild impairment with an improving trajectory (38.3% of patients)
moderate impairment with a stable trajectory (18.4% of the patients)
severe impairment with an improving trajectory (12.3% of patients)
severe impairment with a stable trajectory (31.0% of patients).
The more resilient trajectories, i.e., those of ‘improving trajectory’, were associated with higher parental socioeconomic status, less severe baseline symptoms, better premorbid adjustment, and better baseline verbal and memory functioning.³

Reference:
1. Salagre E, Grande I, Solé B, et al. Exploring risk and resilient profiles for functional impairment and baseline predictors in a 2-year follow-up first-episode psychosis cohort using latent class growth analysis. J Clin Med 2020; 10 (1): 73.