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  • Major depressive disorder (MDD) – Definitions and Diagnosis
  • Definitions of clinical course and treatment outcomes II

Definitions of clinical course and treatment outcomes II

Depression

The terms ‘response’ and ‘remission’ have been used to mean different things in psychiatric research; the most commonly used meanings of these terms in studies of treatment outcomes in people with major depression disorder are given on the slide.1,2

References:
1.Nierenberg AA, DeCecco LM. Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: a focus on treatment-resistant depression. J Clin Psychiatry 2001; 62 (Suppl 16): 5–9.

2.Frank E, Prien RF, Jarrett RB, et al. Conceptualization and rationale for consensus definitions of terms in major depressive disorder. Remission, recovery, relapse, and recurrence. Arch Gen Psychiatry 1991; 48 (9): 851–855.

3. Sforzini L, Worrell C, Kose M, et al. A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials. Mol Psychiatry 2022; 27 (3): 1286–1299.

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Published 01.07.2025
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