This slide shows data demonstrating that patients who met the clinical criteria for remission and patients who did not consider themselves to be in remission had significantly greater severity of symptoms and levels of anxiety than those who did, demonstrating that the HAM-D17 definition of remission may not align with the patients’ view of well-being.1,2

References:
1. Zimmerman M, Martinez J, Attiullah N, et al. Symptom differences between depressed outpatients who are in remission according to the Hamilton Depression Rating Scale who do and do not consider themselves to be in remission. J Affect Disord 2012; 142 (1–3): 77–81.

2. Zimmerman M, Martinez J, Attiullah N, et al. Why do some depressed outpatients who are not in remission according to the Hamilton Depression Rating Scale nonetheless consider themselves to be in remission? Depress Anxiety 2012; 29 (10): 891–895.