Emotional lability (pseudobulbar affect)

Emotional lability is thought to result from damage to certain descending pathways in the brain, as detailed on the slide.¹ Such damage can occur in several diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and as a result of stroke.¹

References:
1.Chen JJ. Pharmacotherapeutic management of pseudobulbar affect. Am J Manag Care 2017; 23 (18 Suppl): S345–S350.

2.Miller A, Pratt H, Schiffer RB. Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments. Expert Rev Neurother 2011; 11 (7): 1077–1088.