Studying post-stroke fatigue – the POSITIF study

In the POSITIF study, people who had experienced a stroke were willing to be randomized, although treatment adherence was lower than the authors had hoped.¹ Along with increasing adherence, the authors speculated that the intervention might have been more effective had it been delivered by staff who were already experienced delivering cognitive behavioural therapy.¹ Further work, particularly around intervention design and testing, is needed to understand post-stroke fatigue.¹

Reference:
1.Mead G, Gillespie D, Barber M, et al. Post stroke intervention trial in fatigue (POSITIF): randomised multicentre feasibility trial. Clin Rehabil 2022; 36 (12): 1578–1589.