The direct costs of PD care increase over decades with advancing age, mainly due to worsening disease severity.1 Evidence from a study conducted within the Spanish healthcare system suggests that the increase in costs (direct and indirect) can be considerable, even in the earlier stages of PD.1 An association of increased cost with disease progression was reported; motor symptoms, cognitive impairment, and pain had a direct impact on cost.1

References:
1.Martinez-Martín P, Rodriguez-Blazquez C, Paz S, et al. Parkinson symptoms and health related quality of life as predictors of costs: a longitudinal observational study with linear mixed model analysis. PLoS One 2015; 10 (12): e0145310.