The conundrum of treating schizophrenia – iv

These slides outline the conundrum of treating schizophrenia – in the ‘normal’ brain the levels of dopamine in the mesolimbic and mesocortical pathways are in balance.^{[Stahl, 2013]} However, in the brain of a patient with schizophrenia, the levels are out of balance, with levels in the mesolimbic pathway too high and levels in the mesocortical pathway too low.^{[Stahl, 2013]}

Reference:
Stahl SM. Stahl’s Essential Psychopharmacology. Neuroscientific Basis and Practical Applications. Fourth Edition. © Cambridge University Press, 2013.