Comorbidities of alcohol use modelled in England and Wales

This study used data from multiple sources to estimate death rates and alcohol consumption in England and Wales in 1997.^[3] As shown on the slide, the analysis found different dose–response relationships between alcohol consumption and risk of death from many different diseases.^[3] Other analyses have focused on particular harms, e.g., showing that alcohol consumption increases the risk of specific cancers.^[1] Some have argued the case for a long-term study of the effect of moderate alcohol consumption on chronic disease, to test the correlation of alcohol with preventing or causing disease.^[2]

References:

[1] Jayasekara H, MacInnis RJ, Room R, English DR. Long-term alcohol consumption and breast, upper aero–digestive tract and colorectal cancer risk: a systematic review and meta-analysis. Alcohol Alcohol 2016; 51 (3): 315–330.

[2] Mukamal KJ, Clowry CM, Murray MM, et al. Moderate alcohol consumption and chronic disease: the case for a long-term trial. Alcohol Clin Exp Res 2016; 40 (11): 2283–2291.

[3] White IR, Altmann DR, Nanchahal K. Alcohol consumption and mortality: modelling risks for men and women at different ages. BMJ 2002; 325 (7357): 191.