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This article discusses the modifiable risk factors for dementia and what actions individuals can take to minimize their dementia risk.
This article reviews novel pharmacologic agents, summarizing their proposed mechanism of action (MOA) and currently available clinical data, putting these developments into the context of treatment gaps, clinical trial methodology, and required further real-world evaluation.
This article discusses the latest advances in psychiatric genetics, focusing on MDD, the use of PRS in research, and potential future clinical practice applications.
Definitive diagnosis of AD requires an autopsy evaluation of the brain to investigate the presence of amyloid-β plaques and tau neurofibrillary tangles. If these brain pathologies are observed in various brain regions, a diagnosis of AD can be made.
Based on a body of literature on striatal function and treatment response, multiple neuroimaging prognostic biomarkers have been developed, of which two seem to have the most data for internal and external validation.
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