Neuroimaging differences between patients with prodromal symptoms who do and do not later develop psychosis

Researchers have found that prodromal patients who develop psychosis show (A) smaller medial temporal volume, (B) reduced white matter integrity in fronto-temporal fibers, (C) increased activation in medial temporal and prefrontal cortex and in the midbrain, and (D) increased dopamine synthesis in the striatum.

Source. David Nutt, Imperial College London.

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