The impact of an opioid receptor antagonist/partial agonist to reduce fMRI BOLD activity in the striatum when people with alcohol dependence engage in the MID task [see also fig 4]. Difference is contrast with the activity seen on placebo. In both scans blood alcohol concentration was held at 80 mg%.7
Related content
Major depressive disorder (MDD) – Treatment principles
This slide deck covers the treatment principles of Major Depressive Disorder (MDD).
12.06.2025
Depression
The basal ganglia
The basal ganglia regulate movement through dopaminergic input from the SNc to the striatum, modulating motor signals via direct and indirect pathways.
04.06.2025
Parkinson’s Disease
Dopamine’s action on receptors in the striatum
Dopamine modulates movement by acting on D1 and D2 receptors in the striatum, influencing excitatory and inhibitory motor pathways.
04.06.2025
Parkinson’s Disease