Based on a systematic review and random-effects meta-analysis of 135 studies (1957–2021), including 4.5 million people with schizophrenia and over 1.1 billion general population controls, all-cause mortality was higher in people with schizophrenia than in the general population (incident schizophrenia risk ratio: 3.516 [95% CI: 3.09, 3.998]; prevalent schizophrenia risk ratio: 2.859 [95% CI: 2.622, 3.117]).1
Abbreviations: CI=confidence interval
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