References:
1. Merritt K, Luque Laguna P, Irfan A, et al. Longitudinal structural MRI findings in individuals at genetic and clinical high risk for psychosis: a systematic review. Front Psychiatry 2021; 12: 620401.
2. ENIGMA Clinical High Risk for Psychosis Working Group; Jalbrzikowski M, Hayes RA, et al. Association of structural magnetic resonance imaging measures with psychosis onset in individuals at clinical high risk for developing psychosis: an ENIGMA Working Group mega-analysis. JAMA Psychiatry 2021;78: 753–766.
3. Vita A, De Peri L, Deste G, et al. Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies. Transl Psychiatry 2012; 2: e190.
Structural differences are evident in the brain before psychosis onset
