Timing of psychiatric comorbidities in schizophrenia

The figure presents a matrix of HRs showing how receiving one psychiatric diagnosis affects the risk of subsequently receiving another among 5,432 individuals with schizophrenia.¹ This analysis captures temporal ordering, that is, which comorbidities tend to appear before others in the clinical trajectory.¹

Abbreviation:
HR=hazard ratio

Reference:
1. Krebs MD, Themudo GE, Benros ME, et al. Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors. Nat Commun 2021; 12: 6617.