A meta-analysis of data from relapse prevention studies found that discontinuation of antidepressant treatment increased the risk of relapse by more than threefold and reduced the time to relapse when compared with treatment continuation.1

Reference:
1. Batelaan NM, Bosman RC, Muntingh A, et al. Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. BMJ 2017; 358: j3927.