Clinical staging models in BD – Berk et al. 2007 model

Several staging models have been developed to study and describe the severity of bipolar disorder, including the Berk et al. model, the Kapczinski et al. model, and the Duffy et al. model.¹ The Berk et al. model, published in 2007, incorporated the prodromal stages of the condition, emphasizing early detection to allow for early intervention.²

References:
1. Kupka R, Duffy A, Scott J, et al. Consensus on nomenclature for clinical staging models in bipolar disorder: a narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force. Bipolar Disord 2021; 23 (7): 659–678.
2. Berk M, Conus P, Lucas N, et al. Setting the stage: from prodrome to treatment resistance in bipolar disorder. Bipolar Disord 2007; 9 (7): 671–678.