Bipolar disorder is a highly heritable condition, as are many other psychiatric disorders, such as schizophrenia.1-3 Decades of research into the genetics of disorders such as bipolar disorder and schizophrenia have identified and corroborated several genetic loci implicated in these disorders.3,4
References:
1. Carroll LS, Owen MJ. Genetic overlap between autism, schizophrenia and bipolar disorder. Genome Med 2009; 1 (10): 102.
2. Lichtenstein P, Yip BH, Björk C, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 2009; 373 (9659): 234–239.
3. Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder and Schizophrenia Working
4. Group of the Psychiatric Genomics Consortium. Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 2018; 173 (7): 1705–1715.
5. Craddock N, O’Donovan MC, Owen MJ. The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet 2005; 42 (3): 193–204.