Neuropsychiatric comorbidities occur in approximately 70% of people with MDD – this prevalence generally increases with depression severity, ranging from 64% comorbidity prevalence rate in people with mild depression to a 78% prevalence rate in people with severe MDD.1,2
References:
1.Steffen A, Nübel J, Jacobi F, et al. Mental and somatic comorbidity of depression: a comprehensive cross-sectional analysis of 202 diagnosis groups using German nationwide ambulatory claims data. BMC Psychiatry 2020; 20: 142.
2.Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003; 289 (23): 3095–3105.
3.Arnaud AM, Brister TS, Duckworth K, et al. Impact of major depressive disorder on comorbidities: A systematic literature review. J Clin Psychiatry 2022; 83 (6): 21r14328.
