Inadequate or partial response to first line treatment

As outlined on the slide, inadequate or partial response to treatment increases the risk of relapse.^1-3

References:
1.Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 2006; 163 (11): 1905–1917.

2.Kennedy SH. A review of antidepressant therapy in primary care: current practices and future directions. Prim Care Companion CNS Disord 2013; 15 (2): PCC.12r01420.

3.Conradi HJ, Ormel J, de Jonge, P. Presence of individual (residual) symptoms during depressive episodes and periods of remission: a 3-year prospective study. Psychological Medicine 2011; 41 (6): 1165–1174.