As with other psychiatric diagnoses, the long-term outcomes of major depressive disorder range from complete remission to a chronic syndrome.1
References:
1.Verduijn J, Verhoeven JE, Milaneschi Y, et al. Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule. BMC Med 2017; 15 (1): 215.
2.Ten Have M, Tuithof M, van Dorsselaer S, et al. How chronic are depressive and anxiety disorders? 9-year general population study using narrow and broad course outcomes. J Affect Disord 2022; 317: 149–155.
3.Cuijpers P, Vogelzangs N, Twisk J, et al. Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. Am J Psychiatry 2014; 171 (4): 453–462.