From the perspective of the patient, viewing migraine as a neural condition is potentially a good thing.[Goadsby, 2009] The generation of vasoactive drugs that have been used in the treatment of migraine have the potential to cause vascular complications.[Goadsby, 2009] Triptans, for example, carry prescribing precautions for individuals at risk of heart disease, who have cerebrovascular complications, or who have high blood pressure.[Imigran SPC, 2019] Targeting the neurological processes underlying migraine, therefore, might lead to therapeutic options unhindered by vascular contraindications.[Goadsby, 2009]
Imigran Radis 100 mg tablets. Summary of product characteristics. GlaxoSmithKline UK, October 2019.
Other references used on slide:
Burstein R, Noseda R, Borsook D. Migraine: multiple processes, complex pathophysiology. J Neurosci 2015; 35 (17): 6619–6629.