Transmission of pain involves a complex series of interactions, described on the slide.[Steeds, 2016] First-order, afferent neurons convey the signal from the site of injury, and synapse with second-order neurons in the dorsal horn of the spinal cord.[Steeds, 2016] Tracts of neurons ascending the spinal cord convey the signal towards the brain, where it is processed in the thalamus, and sent onwards to the cortex.[Steeds, 2016]
Reference:
Steeds CE. The anatomy and physiology of pain. Surgery 2016; 34 (2): 55–59.
Other references used on slide:
Purves D, Augustine GJ, Fitzpatrick D, et al. Neuroscience, 6th edition. New York, New York: Oxford University Press, 2018.
Urch C. Normal pain transmission. Rev Pain 2007; 1 (1): 2–6.