Treatment guidelines recommend the use of antiemetics as adjunctive therapy – an add on to the antimigraine therapy.[Marmura et al., 2015; Worthington et al., 2013] Certain antiemetics are strongly recommended alongside migraine medication in patients with migraine for the relief of nausea.[Marmura et al., 2015; Worthington et al., 2013]
References:
Marmura MJ, Silberstein SD, Schwedt TJ. The acute treatment of migraine in adults: the American Headache Society evidence assessment of migraine pharmacotherapies. Headache 2015; 55 (1): 3–20.
Worthington I, Pringsheim T, Gawel MJ, et al. Canadian Headache Society Guideline: acute drug therapy for migraine headache. Can J Neurol Sci 2013; 40 (5 Suppl 3): S1–S80.
Other references used on slide:
Hauser JM, Azzam JS, Kasi A. Antiemetic Medications. [Updated 2019 Nov 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020.
Kirthi V, Derry S, Moore RA. Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev 2013; (4): CD008041.
Lyons S, Ballisat B. Antiemetic drugs: pharmacology and an overview of their clinical use. Update Anaesthesia 2016; 31: 38–42. Schulman EA, Dermott KF. Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs. Headache 2003; 43 (7): 729–733.