The MDS diagnostic criteria for MCI in PD represent an attempt to harmonise the various definitions of MCI in PD that have been used in the past.1 A uniform definition allows identification of:1

  • the clinical characteristics of the earliest stage of PD cognitive impairment
  • the best predictors of conversion from PD–MCI to PD dementia
  • the effects of PD–MCI on the quality of life and day-to-day functioning of patients with PD
  • a well-characterised patient population, and a potential outcome measure, for clinical trials
  • a useful clinical entity that will allow clinicians, patients, caregivers, and researchers to communicate better, thereby improving patient care and research efforts.

References:
1. Litvan I, Goldman JG, Tröster AI, et al. Diagnostic criteria for mild cognitive impairment in Parkinson’s disease: Movement Disorder Society task force guidelines. Mov Disord 2012; 27 (3): 349–356.

2. Emre M, Aarsland D, Brown R, et al. Clinical diagnostic criteria for dementia associated with Parkinson’s disease. Mov Disord 2007; 22 (12): 1689–1707.