.jpg)
The correction of the results for potentially confounding variables in this study was an important control step.[Crump et al., 2013] The variables that were adjusted for included: age, marital status, education level, employment status, and income.[Crump et al., 2013] Separately, the mediating effect of substance use was modelled, by including in the calculations any diagnosis of alcohol-use disorder or substance-use disorders (according to ICD-10 codes).[Crump et al., 2013]
The study also analysed all-cause mortality over the seven years of the study, from January 2003 to December 2009.[Crump et al., 2013] The association between schizophrenia and all-cause mortality was stronger among women, the employed, and those without substance-use disorders.[Crump et al., 2013] Schizophrenia was strongly associated with an elevated mortality, the leading causes of which were ischaemic heart disease, and cancer.[Crump et al., 2013]
References:
Crump C, Winkleby MA, Sundquist K, Sundquist J. Comorbidities and mortality in persons with schizophrenia: a Swedish national cohort study. Am J Psychiatry 2013; 170 (3): 324–333.
Ripoll OP, Pedersen C, Agerbo E, et al. A comprehensive nationwide study of comorbidity within treated mental disorders – a Danish register-based study. Schizophr Bull 2018; 44 (Suppl 1): S87.