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Key message: Inability of patients to function in everyday settings contributes to the high cost of schizophrenia (both direct costs from caring for patients, and indirect costs from lost employment).
Background
- Schizophrenia causes a high degree of disability. In the global burden of disease study, schizophrenia accounted for 1.1% of the total disability-adjusted life years (DALYs) and 2.8% of years lived with disability (YLD).[WHO, 2001]
- Annual cost of schizophrenia is over €110 billion per year in the EU and US alone (calculated total from France, Germany, Hungary, Norway, UK, US). 2.5% of national health expenditure in US represents both direct and indirect costs of schizophrenia.[Knapp et al., 2004]
- Baseline data on more than 1,400 patients with a diagnosis of schizophrenia were collected before their entry into the Clinical Antipsychotic Trial of Intervention Effectiveness (CATIE) schizophrenia study. 72.9% of patients reported no employment activity. Overall employment of persons with schizophrenia seems to be impeded by clinical problems, including symptoms of schizophrenia and poorer neurocognitive and intrapsychic functioning.[Rosenheck et al., 2006]
Note on Knapp reference: please note that more recent figures for similar statistics are available and have been published. The Knapp reference was used for this slide as the most relevant and widely cited source.
References:
World Health Organization (WHO). The World Health Report 2001 – Mental Health: New Understanding, New Hope. 2001.
Knapp M, et al. Schizophr Bull 2004; 30 (2): 279–293.
Rosenheck R, et al. Am J Psychiatry 2006; 163: 411–417.
Harvey PD, Strassnig M. World Psychiatry 2012; 11: 73–79.