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  • The debate around relapses and supersensitivity psychosis being ‘toxic’ for the brain (II)

The debate around relapses and supersensitivity psychosis being ‘toxic’ for the brain (II)

Schizophrenia
The debate around relapses and supersensitivity psychosis being ‘toxic’ for the brain

References:

1. Takeuchi H, Siu C, Remington G, et al. Does relapse contribute to treatment resistance? Antipsychotic response in first- vs. second-episode schizophrenia. Neuropsychopharmacology 2018; 44: 1036–1042.

2. Silvestri S, Seeman MV, Negrete JC, et al. Increased dopamine D2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study. Psychopharmacology (Berl) 2000; 152: 174–180.

3. Ginovart N, Wilson AA, Hussey D, et al. D2-receptor upregulation is dependent upon temporal course of D2-occupancy: a longitudinal [11C]-raclopride PET study in cats. Neuropsychopharmacology 2009; 34: 662–671.

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Published 04.08.2026
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