Pharmacological therapies for addictive disorders

There are many pharmacological therapies that are used in the treatment of various substance disorders, including nicotine addictions as well as alcohol- and opiate-use disorders as shown on the slide.² There are still many unknowns of addiction pharmacotherapy, such as how combination therapies might best be used, and how to best match specific patients with specific therapies, that may be addressed by future research.²

Reference:
[1] Fagerström KO, Jiménez-Ruiz CA. Pharmacological treatments for tobacco dependence. Eur Respir Rev 2008; 17 (110): 192–198

[2] Douaihy AB, Kelly TM, Sullivan C. Medications for substance use disorders. Soc Work Public Health 2013; 28 (3–4): 264–278.

[3] Stokłosa I, Więckiewicz G, Stokłosa M, et al. Medications for the treatment of alcohol dependence – current state of knowledge and future perspectives from a public health perspective. Int J Environ Res Public Health 2023; 20 (3): 1870.

[4] Ivan Ezquerra-Romano I, Lawn W, Krupitsky E, Morgan CJA. Ketamine for the treatment of addiction: evidence and potential mechanisms. Neuropharmacology 2018; 142: 72–82.