Historically, approaches to illicit substances have encompassed a spectrum ranging from open use to prohibition.3 The 20th century is full of examples of national, and international, attempts to control the use and trade of substances of abuse, including opium and alcohol.3 More recently, the focus of many policy makers and healthcare providers across the world has been to move to a harm-reduction model.3,4 The British Association for Psychopharmacology (BAP) has developed evidence-based consensus guidelines for the pharmacological management of substance-use disorders and other addictions, which are outlined on the slide.4

References:
[1] Rosenthal RJ, Faris SB. The etymology and early history of ‘addiction’. Addict Res Theory 2019; 27 (5): 437–449.

[2] Crocq MA. Historical and cultural aspects of man’s relationship with addictive drugs. Dialogues Clin Neurosci 2007; 9 (4): 355–361.

[3] Gomes TB, Vecchia MD. Harm reduction strategies regarding the misuse of alcohol and other drugs: a review of the literature. Cien Saude Colet 2018; 23 (7): 2327–2338.

[4] Lingford-Hughes AR, Welch S, Peters L, Nutt DJ; British Association for Psychopharmacology, Expert Reviewers Group. BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP. J Psychopharmacol 2012; 26 (7): 899–952.