Professor David Nutt provides insights to enhance our understanding of the treatment of substance use disorders and other addictions.
In this video, you can learn about the greatest challenges of treating substance use disorders. Professor David Nutt discusses what the most significant harms of substance use disorders are. Also, you will discover the latest advancements for treating substance use disorders.
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Current evidence on the neurobiology of addictive behaviour highlights the transition from reward-driven to habitual drug use through alterations in mesolimbic dopamine, glutamatergic signalling, frontostriatal circuitry, and stress-related systems.
Functional neuroimaging studies commonly compare brain responses to substance-related cues versus neutral cues during fMRI or PET scanning and measure differential brain activation.
Recognition of addiction as a disorder of distributed brain circuits provides a framework for personalized assessment and treatment of addiction.