The idea of early intervention in bipolar disorder is gaining momentum.1 Indeed, the idea of preventing disease progression in a condition that is associated with a substantial burden of morbidity and mortality is a very attractive prospect.1 However, in order to fully realize the goal of preventing bipolar disorder, more research into what interventions work best, and into identifying valid biomarkers of disease, are needed.1
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Bipolar disorder (BD) includes several disorders of emotion, thought, and energy, characterized by biphasic mood episodes of mania or hypomania and depression.