Competitive antagonists shift the dose-effect curve for an agonist (e.g. the endogenous neurotransmitter) to the right, but this effect can eventually be overcome by enough agonist concentration.
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The olfactory system detects airborne odor molecules in the nasal cavity and transmits this information to the olfactory bulb. From there, signals are relayed to several brain regions involved in smell perception, memory, emotion, and behaviour.
The gustatory system detects taste stimuli on the tongue and relays this information through brainstem and thalamic pathways to the gustatory cortex.