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  • Schizophrenia – Course, Natural History and Prognosis
  • Treatment adherence and relapse risk

Treatment adherence and relapse risk

Schizophrenia
Slide showing the relationship between treatment adherence and relapse risk across the course of schizophrenia

References:
1. Caseiro O, Pérez-Iglesias R, Mata I, et al. Predicting relapse after a first episode of non-affective psychosis: a three-year follow-up study. J Psychiatr Res 2012; 46: 1099–1105.
2. Kishi T, Ikuta T, Matsui Y, et al. Effect of discontinuation v. maintenance of antipsychotic medication on relapse rates in patients with remitted/stable first-episode psychosis: a meta-analysis. Psychol Med 2019; 49: 772–779.
3. Bogers JPAM, Hambarian G, Schmidt N, et al. Risk factors for psychotic relapse after dose reduction or discontinuation of antipsychotics in patients with chronic schizophrenia. A meta-analysis of randomized controlled trials. Schizophr Bull 2023; 49: 11–23.

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Published 08.06.2026
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